Low temperature combined with low light (LL) is an adverse factor seriously affecting pepper productivity and quality.However, little is known about the molecular mechanisms related to LL stress responses.Therefore, transcriptome and physiological changes in Hangjiao No.2 (H2) and Xiangtela No.2 (X2) Honeysuckle pepper were studied under normal con
Origin and evolution of false brinelling and fretting corrosion under rolling conditions
Abstract Rolling bearings working in oscillating applications often suffer from false brinelling and fretting corrosion that limit their service life.At present, the study of oscillation-induced failures is primarily dominated by a large number of sliding and bench tests.However, most of the previous work are not able to fully describe the two clos
Targeting active RAS with molecular glue
Activating mutations in RAS genes, notably KRASG12C, are pervasive Cake Stand in numerous cancers, presenting formidable challenges to therapy due to their elusive druggability.The landmark discovery of KRASG12C allosteric inhibitors marked a transformative milestone in cancer treatment, resulting in the approval of sotorasib and adagrasib.However,
Genetic labeling reveals spatial and cellular expression pattern of neuregulin 1 in mouse brain
Abstract Background Where the gene is expressed determines the function of the Corn Flour gene.Neuregulin 1 (Nrg1) encodes a tropic factor and is genetically linked with several neuropsychiatry diseases such as schizophrenia, bipolar disorder and depression.Nrg1 has broad functions ranging from regulating neurodevelopment to neurotransmission in th
Political Aspects of Digitalization and Networking of the State
The digitalization of the state is the object of close scientific discourse, especially in terms of the implementation of administrative reforms and the description of the storyline of the formation and development of M Vest new tools and forms in modern public administration.A meaningful analysis of an extensive layer of scientific publications sh